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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2B
All Species:
17.88
Human Site:
S71
Identified Species:
26.22
UniProt:
P31323
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31323
NP_002727.2
418
46302
S71
A
A
G
G
G
T
P
S
K
G
V
N
F
A
E
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
S130
A
A
G
G
G
T
P
S
K
G
V
N
F
A
E
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
G111
S
A
A
A
V
G
G
G
T
P
S
K
G
V
N
Dog
Lupus familis
XP_849179
417
46163
S71
A
A
G
G
G
T
P
S
K
G
V
N
F
A
E
Cat
Felis silvestris
Mouse
Mus musculus
P31324
416
46149
S71
A
A
G
G
G
I
P
S
K
G
V
N
F
A
E
Rat
Rattus norvegicus
P12369
416
46104
S71
A
A
G
G
G
T
P
S
K
G
V
N
F
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
A24
D
L
G
V
C
A
E
A
Y
N
P
D
E
E
E
Chicken
Gallus gallus
Q5ZM91
382
43332
N67
E
E
T
K
Q
L
L
N
Q
Q
K
S
G
S
R
Frog
Xenopus laevis
NP_001084637
402
45172
M71
N
F
A
E
E
P
S
M
Q
T
D
S
E
N
G
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
N71
E
P
M
Q
T
E
S
N
G
D
E
D
D
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
N66
T
D
D
Q
L
S
V
N
S
Q
D
A
D
A
E
Honey Bee
Apis mellifera
XP_392905
383
43849
I76
S
V
D
E
E
P
P
I
I
K
L
A
T
R
R
Nematode Worm
Caenorhab. elegans
P30625
366
41449
A66
E
G
G
N
P
D
A
A
D
D
D
D
I
I
V
Sea Urchin
Strong. purpuratus
Q26619
369
41770
E67
A
E
S
D
I
D
D
E
P
P
E
L
P
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
A75
S
F
S
R
P
Q
S
A
Q
S
Q
S
R
S
R
Red Bread Mold
Neurospora crassa
Q01386
385
42138
P75
D
M
P
V
R
R
Q
P
D
D
F
P
A
H
Y
Conservation
Percent
Protein Identity:
100
86.5
90
96.6
N.A.
97.1
96.8
N.A.
70.3
34.6
78.4
68.1
N.A.
44
47.6
31.8
50.9
Protein Similarity:
100
87.2
90.2
98
N.A.
98
98.5
N.A.
74.1
52.3
85.4
80.6
N.A.
64.1
63.8
50.9
66.5
P-Site Identity:
100
100
6.6
100
N.A.
93.3
100
N.A.
13.3
0
0
0
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
100
N.A.
26.6
26.6
13.3
20
N.A.
26.6
20
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
36.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
38
13
7
0
7
7
19
0
0
0
13
7
38
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
7
13
7
0
13
7
0
13
19
19
19
13
0
7
% D
% Glu:
19
13
0
13
13
7
7
7
0
0
13
0
13
13
44
% E
% Phe:
0
13
0
0
0
0
0
0
0
0
7
0
32
0
0
% F
% Gly:
0
7
44
32
32
7
7
7
7
32
0
0
13
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
7
7
0
7
7
0
0
0
7
7
0
% I
% Lys:
0
0
0
7
0
0
0
0
32
7
7
7
0
7
0
% K
% Leu:
0
7
0
0
7
7
7
0
0
0
7
7
0
0
0
% L
% Met:
0
7
7
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
7
0
0
0
19
0
7
0
32
0
7
13
% N
% Pro:
0
7
7
0
13
13
38
7
7
13
7
7
7
0
0
% P
% Gln:
0
0
0
13
7
7
7
0
19
13
7
0
0
0
0
% Q
% Arg:
0
0
0
7
7
7
0
0
0
0
0
0
7
7
19
% R
% Ser:
19
0
13
0
0
7
19
32
7
7
7
19
0
13
0
% S
% Thr:
7
0
7
0
7
25
0
0
7
7
0
0
7
0
0
% T
% Val:
0
7
0
13
7
0
7
0
0
0
32
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _